APLP2 FISH Probe
The APLP2 FISH probe is designed to hybridize to the APLP2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APLP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| APLP2-20-RE | 20 (40 μL) | 200 μL |  |
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| APLP2-20-GO | 20 (40 μL) | 200 μL |  |
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| APLP2-20-GR | 20 (40 μL) | 200 μL |  |
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| APLP2-20-AQ | 20 (40 μL) | 200 μL |  |
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| APLP2-20-DIG | 20 (40 μL) | 200 μL |  |
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| APLP2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: APLP2
Gene Name: Amyloid Beta Precursor Like Protein 2
Chromosome: CHR11: 129939715-130014706
Locus: 11q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APLP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APLP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping