APLE FISH Probe
The APLE FISH probe is designed to hybridize to the APLE gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CES1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CES1-20-RE | 20 (40 μL) | 200 μL |  |
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| CES1-20-GO | 20 (40 μL) | 200 μL |  |
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| CES1-20-GR | 20 (40 μL) | 200 μL |  |
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| CES1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CES1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CES1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Details
Gene Symbol: CES1
Gene Name: Carboxylesterase 1
Chromosome: CHR16: 55836763-55867075
Locus: 16q12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: APLE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CES1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping