APE2 FISH Probe
The APE2 FISH probe is designed to hybridize to the APE2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APEX2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| APEX2-20-RE | 20 (40 μL) | 200 μL |  |
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| APEX2-20-GO | 20 (40 μL) | 200 μL |  |
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| APEX2-20-GR | 20 (40 μL) | 200 μL |  |
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| APEX2-20-AQ | 20 (40 μL) | 200 μL |  |
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| APEX2-20-DIG | 20 (40 μL) | 200 μL |  |
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| APEX2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
Gene Details
Gene Symbol: APEX2
Gene Name: Apurinic/apyrimidinic Endodeoxyribonuclease 2
Chromosome: CHRX: 55026779-55034212
Locus: Xp11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APE2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APEX2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping