APE FISH Probe
The APE FISH probe is designed to hybridize to the APE gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APEX1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| APEX1-20-RE | 20 (40 μL) | 200 μL |  |
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| APEX1-20-GO | 20 (40 μL) | 200 μL |  |
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| APEX1-20-GR | 20 (40 μL) | 200 μL |  |
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| APEX1-20-AQ | 20 (40 μL) | 200 μL |  |
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| APEX1-20-DIG | 20 (40 μL) | 200 μL |  |
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| APEX1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: APEX1
Gene Name: Apurinic/apyrimidinic Endodeoxyribonuclease 1
Chromosome: CHR14: 20923289-20925931
Locus: 14q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APEX1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping