APC Break Apart FISH Probe
Empire Genomics’ APC Break Apart FISH Probe is designed to flank the APC gene and is typically used for detecting APC rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APCBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APCBA-20-AQOR | 20 (40 μL) | 200 μL |
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| APCBA-20-GOGR | 20 (40 μL) | 200 μL |
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| APCBA-20-GORE | 20 (40 μL) | 200 μL |
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| APCBA-20-GRGO | 20 (40 μL) | 200 μL |
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| APCBA-20-GROR | 20 (40 μL) | 200 μL |
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| APCBA-20-GRRE | 20 (40 μL) | 200 μL |
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| APCBA-20-REGO | 20 (40 μL) | 200 μL |
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| APCBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: APC
Gene Name: APC, WNT Signaling Pathway Regulator
Chromosome: CHR5: 112043201-112181936
Locus: 5q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping