APC FISH Probe
The APC FISH probe is designed to hybridize to the APC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| APC-20-RE | 20 (40 μL) | 200 μL |  |
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| APC-20-GO | 20 (40 μL) | 200 μL |  |
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| APC-20-GR | 20 (40 μL) | 200 μL |  |
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| APC-20-AQ | 20 (40 μL) | 200 μL |  |
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| APC-20-DIG | 20 (40 μL) | 200 μL |  |
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| APC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: APC
Gene Name: APC, WNT Signaling Pathway Regulator
Chromosome: CHR5: 112043201-112181936
Locus: 5q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: APC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping