AOS5 FISH Probe
The AOS5 FISH probe is designed to hybridize to the AOS5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NOTCH1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NOTCH1-20-RE | 20 (40 μL) | 200 μL |  |
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| NOTCH1-20-GO | 20 (40 μL) | 200 μL |  |
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| NOTCH1-20-GR | 20 (40 μL) | 200 μL |  |
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| NOTCH1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NOTCH1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NOTCH1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: NOTCH1
Gene Name: Notch 1
Chromosome: CHR9: 139388895-139440238
Locus: 9q34.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AOS5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NOTCH1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping