ANTITHROMBIN, AT-III FISH Probe
The ANTITHROMBIN, AT-III FISH probe is designed to hybridize to the ANTITHROMBIN, AT-III gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SERPINC1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SERPINC1-20-RE | 20 (40 μL) | 200 μL |  |
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| SERPINC1-20-GO | 20 (40 μL) | 200 μL |  |
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| SERPINC1-20-GR | 20 (40 μL) | 200 μL |  |
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| SERPINC1-20-AQ | 20 (40 μL) | 200 μL |  |
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| SERPINC1-20-DIG | 20 (40 μL) | 200 μL |  |
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| SERPINC1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009]
Gene Details
Gene Symbol: SERPINC1
Gene Name: Serpin Family C Member 1
Chromosome: CHR1: 173872941-173886516
Locus: 1q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ANTITHROMBIN, AT-III FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SERPINC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping