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ANPR-A FISH Probe

The ANPR-A FISH probe is designed to hybridize to the ANPR-A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NPR1-20-OR  (Standard Design) 20 (40 μL) 200 μL
NPR1-20-RE 20 (40 μL) 200 μL
NPR1-20-GO 20 (40 μL) 200 μL
NPR1-20-GR 20 (40 μL) 200 μL
NPR1-20-AQ 20 (40 μL) 200 μL
NPR1-20-DIG 20 (40 μL) 200 μL
NPR1-20-BIO 20 (40 μL) 200 μL

Gene Summary

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009]

Gene Details

Gene Symbol: NPR1

Gene Name: Natriuretic Peptide Receptor 1

Chromosome: CHR1: 153651163-153666468

Locus: 1q21.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ANPR-A FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: NPR1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping