ANPEP FISH Probe
The ANPEP FISH probe is designed to hybridize to the ANPEP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANPEP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ANPEP-20-RE | 20 (40 μL) | 200 μL |  |
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| ANPEP-20-GO | 20 (40 μL) | 200 μL |  |
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| ANPEP-20-GR | 20 (40 μL) | 200 μL |  |
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| ANPEP-20-AQ | 20 (40 μL) | 200 μL |  |
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| ANPEP-20-DIG | 20 (40 μL) | 200 μL |  |
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| ANPEP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ANPEP
Gene Name: Alanyl Aminopeptidase, Membrane
Chromosome: CHR15: 90328125-90358072
Locus: 15q26.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ANPEP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ANPEP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping