ANKB FISH Probe
The ANKB FISH probe is designed to hybridize to the ANKB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ANK2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
ANK2-20-RE | 20 (40 μL) | 200 μL | ||
ANK2-20-GO | 20 (40 μL) | 200 μL | ||
ANK2-20-GR | 20 (40 μL) | 200 μL | ||
ANK2-20-AQ | 20 (40 μL) | 200 μL | ||
ANK2-20-DIG | 20 (40 μL) | 200 μL | ||
ANK2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]
Gene Details
Gene Symbol: ANK2
Gene Name: Ankyrin 2
Chromosome: CHR4: 113739238-114304896
Locus: 4q25-q26
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: ANKB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ANK2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping