AML1-EVI-1 FISH Probe
The AML1-EVI-1 FISH probe is designed to hybridize to the AML1-EVI-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MECOM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MECOM-20-RE | 20 (40 μL) | 200 μL |  |
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| MECOM-20-GO | 20 (40 μL) | 200 μL |  |
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| MECOM-20-GR | 20 (40 μL) | 200 μL |  |
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| MECOM-20-AQ | 20 (40 μL) | 200 μL |  |
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| MECOM-20-DIG | 20 (40 μL) | 200 μL |  |
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| MECOM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Details
Gene Symbol: MECOM
Gene Name: MDS1 And EVI1 Complex Locus
Chromosome: CHR3: 168801286-169381563
Locus: 3q26.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: AML1-EVI-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MECOM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping