AMDM FISH Probe
The AMDM FISH probe is designed to hybridize to the AMDM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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NPR2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
NPR2-20-RE | 20 (40 μL) | 200 μL | ||
NPR2-20-GO | 20 (40 μL) | 200 μL | ||
NPR2-20-GR | 20 (40 μL) | 200 μL | ||
NPR2-20-AQ | 20 (40 μL) | 200 μL | ||
NPR2-20-DIG | 20 (40 μL) | 200 μL | ||
NPR2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NPR2
Gene Name: Natriuretic Peptide Receptor 2
Chromosome: CHR9: 35792405-35809728
Locus: 9p13.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AMDM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NPR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping