AMACR FISH Probe
The AMACR FISH probe is designed to hybridize to the AMACR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AMACR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AMACR-20-RE | 20 (40 μL) | 200 μL |  |
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| AMACR-20-GO | 20 (40 μL) | 200 μL |  |
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| AMACR-20-GR | 20 (40 μL) | 200 μL |  |
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| AMACR-20-AQ | 20 (40 μL) | 200 μL |  |
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| AMACR-20-DIG | 20 (40 μL) | 200 μL |  |
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| AMACR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
Gene Details
Gene Symbol: AMACR
Gene Name: Alpha-methylacyl-CoA Racemase
Chromosome: CHR5: 33987090-34008220
Locus: 5p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AMACR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AMACR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping