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ALX4 FISH Probe

The ALX4 FISH probe is designed to hybridize to the ALX4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ALX4-20-OR  (Standard Design) 20 (40 μL) 200 μL
ALX4-20-RE 20 (40 μL) 200 μL
ALX4-20-GO 20 (40 μL) 200 μL
ALX4-20-GR 20 (40 μL) 200 μL
ALX4-20-AQ 20 (40 μL) 200 μL
ALX4-20-DIG 20 (40 μL) 200 μL
ALX4-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, cognitive disability, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]

Gene Details

Gene Symbol: ALX4

Gene Name: ALX Homeobox 4

Chromosome: CHR11: 44282277-44331716

Locus: 11p11.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ALX4 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ALX4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping