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ALX4 FISH Probe

The ALX4 FISH probe is designed to hybridize to the ALX4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ALX4-20-OR  (Standard Design) 20 (40 μL) 200 μL
ALX4-20-RE 20 (40 μL) 200 μL
ALX4-20-GO 20 (40 μL) 200 μL
ALX4-20-GR 20 (40 μL) 200 μL
ALX4-20-AQ 20 (40 μL) 200 μL
ALX4-20-DIG 20 (40 μL) 200 μL
ALX4-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, cognitive disability, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]

Gene Details

Gene Symbol: ALX4

Gene Name: ALX Homeobox 4

Chromosome: CHR11: 44282277-44331716

Locus: 11p11.2

Gene Diseases

The ALX4 gene has been associated with the following diseases:

Disease Name
2-Hydroxyglutaricaciduria
49,XXXXX Syndrome
Aagenaes Syndrome
Abderhalden-Kaufmann-Lignac Syndrome
Achard Syndrome
Achard-Thiers Syndrome
Acrocephalopolydactylous Dysplasia
Acrootoocular Syndrome
Acrorenal Syndrome
Akaba Hayasaka Syndrome
Akesson Syndrome
Aloi Tomasini Isaia Syndrome
Alopecia
Alsing Syndrome
Ameloonychohypohidrotic Syndrome
Ansell Bywaters Elderking Syndrome
Arakawa Syndrome 2
AREDYLD Syndrome
Arima Syndrome
Aughton Syndrome
Ayazi Syndrome
BADS Syndrome
Baetz-Greenwalt Syndrome
Bagatelle Cassidy Syndrome
Bangstad Syndrome
Bankart Lesions
Banki Syndrome
Banti's Syndrome
Basaran Yilmaz Syndrome
Bassoe Syndrome
Bazopoulou Kyrkanidou Syndrome
Beardwell Syndrome
Beemer Ertbruggen Syndrome
Bellini Chiumello Rimoldi Syndrome
Biemond Syndrome II
Blepharo-cheilo-dontic Syndrome
Blount Disease
Boerhaave Syndrome
Bone Anteversion
Bone Retroversion
Bonneau Syndrome
Boudhina Yedes Khiari Syndrome
Brachioskeletogenital Syndrome
Brachycephalofrontonasal Dysplasia
Brachymesophalangy 2 And 5
Brunoni Syndrome
CAHMR Syndrome
Calabro Syndrome
Calloso-genital Dysplasia
CAMFAK Syndrome
Cancer
CANOMAD Syndrome
Cantalamessa Baldini Ambrosi Syndrome
Carcinoma
Cardiocranial Syndrome
Carrington Syndrome
CATSHL Syndrome
Cerebelloparenchymal Disorder II
Cerebrooculonasal Syndrome
Chilaiditi Syndrome
CLAPO Syndrome
Cleidorhizomelic Syndrome
Corneodermatoosseous Syndrome
Coxoauricular Syndrome
Cranioacrofacial Syndrome
CRANIOFACIAL ANOMALIES AND ANTERIOR SEGMENT DYSGENESIS SYNDROME
Craniofacial Dyssynostosis
Craniofaciofrontodigital Syndrome
Craniomicromelic Syndrome
Craniotelencephalic Dysplasia
Crome Syndrome
Curatolo Cilio Pessagno Syndrome
Daentl Towsend Siegel Syndrome
Daish Hardman Lamont Syndrome
Daneman Davy Mancer Syndrome
Davenport Donlan Syndrome
Devriendt Syndrome
Dieterich's Disease
Digitorenocerebral Syndrome
Dimauro Disease
Disease
Drachtman Weinblatt Sitarz Syndrome
Dysplasia Epiphysealis Hemimelica
Encephalocele
Epilepsy
Exostoses
Eye Pain
Faciocardiomelic Syndrome
Faciocardiorenal Syndrome
Fairbank Disease
Fetal Trimethadione Syndrome
FLOTCH Syndrome
Flynn Aird Syndrome
Fountain Syndrome
Franceschini Vardeu Guala Syndrome
Freiberg's Disease
Frontoocular Syndrome
Furlong Syndrome
Furukawa Takagi Nakao Syndrome
Gastrocutaneous Syndrome
Gemignani Syndrome
GEMSS Syndrome
Genoa Syndrome
Giacheti Syndrome
Gollop Coates Syndrome
GOMBO Syndrome
Granddad Syndrome
Grover's Disease
Grubben De Cock Borghgraef Syndrome
Gurrieri Sammito Bellussi Syndrome
Hadziselimovic Syndrome
Hagemoser Weinstein Bresnick Syndrome
HAIR-AN Syndrome
Halal Syndrome
Hamanishi Ueba Tsuji Syndrome
Hamano Tsukamoto Syndrome
Hapnes Boman Skeie Syndrome
Hardikar Syndrome
Herrmann Syndrome
Hersh Podruch Weisskopk Syndrome
Hooft Disease
Hordnes Engebretsen Knudtson Syndrome
Human Balantidiasis
Hunt's Syndrome
Hypogonadism
Iida Kannari Syndrome
Infundibulopelvic Dysgenesis
Jagell Holmgren Hofer Syndrome
Kaplowitz Bodurtha Syndrome
Kasabach-Merritt Syndrome
Kashani Strom Utley Syndrome
Katsantoni Papadakou Lagoyanni Syndrome
Kennerknecht Sorgo Oberhoffer Syndrome
Kleeblattschaedel Syndrome
Koone Rizzo Elias Syndrome
Kosztolanyi Syndrome
Krasnow Qazi Syndrome
Kuskokwim Disease
Kuzniecky Syndrome
Kyphomelic Dysplasia
Kyrle Disease
Lachiewicz Sibley Syndrome
Lacrimoauriculodentodigital Syndrome
Lambotte Syndrome
Lelis Syndrome
Lemierre Syndrome
Lung Agenesis
Lyngstadaas Syndrome
Malformations Of Cortical Development, Group I
Malformations Of Cortical Development, Group II
Malouf Syndrome
Manouvrier Syndrome
Marchiafava-Bignami Disease
Marsden Syndrome
Massa Casaer Ceulemans Syndrome
May-Thurner Syndrome
Mehes Syndrome
Melhem Fahl Syndrome
Mengel Konigsmark Syndrome
Merlob Grunebaum Reisner Syndrome
Meyenburg-Altherr-Uehlinger Syndrome
Midphalangeal Hair
Mirizzi Syndrome
Mollica Pavone Antener Syndrome
MOMES Syndrome
Mononen Karnes Senac Syndrome
Morgellons Disease
Nasodigitoacoustic Syndrome
Nathalie Syndrome
Neurofaciodigitorenal Syndrome
Nevo Syndrome
Nicolau Syndrome
Nievergelt Syndrome
Nivelon Nivelon Mabille Syndrome
Oculoauriculofrontonasal Syndrome
Oculocerebrocutaneous Syndrome
Oculodental Syndrome Rutherfurd Syndrome
Oculootofacial Dysplasia
Oculootoradial Syndrome
Oculopalatocerebral Syndrome
Oculopalatoskeletal Syndrome
Oculorenocerebellar Syndrome
Odontomicronychial Dysplasia
Onat Syndrome
Ophthalmomandibulomelic Dysplasia
Oroticaciduria 1
Oslam Syndrome
Otoonychoperoneal Syndrome
OVARIAN DYSGENESIS 3
OVARIAN DYSGENESIS 4
Pain
Parietal Foramina
Parietal Foramina 2
Pascual Castroviejo Syndrome
Pashayan Syndrome
Passovoy Factor
Pavone Fiumara Rizzo Syndrome
Pelviscapular Dysplasia
PHACE Association
Pilotto Syndrome
Piriformis Muscle Syndrome
Piussan Lenaerts Mathieu Syndrome
Podder-Tolmie Syndrome
Postthrombotic Syndrome
Preeyasombat Varavithya Syndrome
Primary Dysautonomias
Propping Zerres Syndrome
Pseudoaminopterin Syndrome
Pseudodiastrophic Dysplasia
Pseudotrisomy 13 Syndrome
Qazi Markouizos Syndrome
Rambaud Galian Syndrome
Ramer Ladda Syndrome
Reginato Schiapachasse Syndrome
Retinohepatoendocrinologic Syndrome
RHYNS Syndrome
Ribbing Disease
Richards-Rundle Syndrome
Rombo Syndrome
Rosselli-Gulienetti Syndrome
Rudiger Syndrome
Sakoda Complex
Salcedo Syndrome
Sammartino De Crecchio Syndrome
Sandifer Syndrome
Satoyoshi Syndrome
Schlegelberger Grote Syndrome
Schofer Beetz Bohl Syndrome
Scholte Syndrome
Schrander-Stumpel Theunissen Hulsmans Syndrome
Seaver Cassidy Syndrome
Seemanova Lesny Syndrome
Sener Syndrome
Shapiro Syndrome
Silengo Lerone Pelizza Syndrome
Sillence Syndrome
Sohval Soffer Syndrome
Splenoportal Vascular Anomalies
Steinfeld Syndrome
Summitt Syndrome
SUNCT Syndrome
Susac Syndrome
Syndrome
Syringomas, Multiple
Tabatznik Syndrome
Thoracolaryngopelvic Dysplasia
Thoracomelic Dysplasia
Tonoki Syndrome
Trichodental Syndrome
Trichoodontoonychial Dysplasia
Trueb Burg Bottani Syndrome
Tsukahara Syndrome
Tucker Syndrome
Upington Disease
Vascular Malformations
Velofacioskeletal Syndrome
Verloove-Vanhorick Brubakk Syndrome
Volcke Soekarman Syndrome
Vomiting
Walbaum Titran Durieux Crepin Syndrome
Waldmann Disease
Warburton Anyane Yeboa Syndrome
Warman Mulliken Hayward Syndrome
Weismann Netter Syndrome
Wyburn Mason's Syndrome
Young McKeever Squier Syndrome
Young Syndrome
Yusho Disease
Zazam Sheriff Phillips Syndrome
Zechi-Ceide Syndrome
Zlotogora-Ogur Syndrome
Zuska's Disease

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ALX4 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ALX4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping