ALX-4 FISH Probe
The ALX-4 FISH probe is designed to hybridize to the ALX-4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALX4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ALX4-20-RE | 20 (40 μL) | 200 μL |  |
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| ALX4-20-GO | 20 (40 μL) | 200 μL |  |
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| ALX4-20-GR | 20 (40 μL) | 200 μL |  |
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| ALX4-20-AQ | 20 (40 μL) | 200 μL |  |
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| ALX4-20-DIG | 20 (40 μL) | 200 μL |  |
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| ALX4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, cognitive disability, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: ALX4
Gene Name: ALX Homeobox 4
Chromosome: CHR11: 44282277-44331716
Locus: 11p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALX-4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALX4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping