ALT1 FISH Probe
The ALT1 FISH probe is designed to hybridize to the ALT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
GPT-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
GPT-20-RE | 20 (40 μL) | 200 μL | ||
GPT-20-GO | 20 (40 μL) | 200 μL | ||
GPT-20-GR | 20 (40 μL) | 200 μL | ||
GPT-20-AQ | 20 (40 μL) | 200 μL | ||
GPT-20-DIG | 20 (40 μL) | 200 μL | ||
GPT-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
Gene Details
Gene Symbol: GPT
Gene Name: Glutamic--pyruvic Transaminase
Chromosome: CHR8: 145729464-145732555
Locus: 8q24.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GPT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping