ALS19 FISH Probe
The ALS19 FISH probe is designed to hybridize to the ALS19 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERBB4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ERBB4-20-RE | 20 (40 μL) | 200 μL |  |
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| ERBB4-20-GO | 20 (40 μL) | 200 μL |  |
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| ERBB4-20-GR | 20 (40 μL) | 200 μL |  |
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| ERBB4-20-AQ | 20 (40 μL) | 200 μL |  |
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| ERBB4-20-DIG | 20 (40 μL) | 200 μL |  |
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| ERBB4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ERBB4
Gene Name: Erb-b2 Receptor Tyrosine Kinase 4
Chromosome: CHR2: 212240441-213403352
Locus: 2q34
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALS19 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ERBB4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping