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ALPL FISH Probe

The ALPL FISH probe is designed to hybridize to the ALPL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ALPL-20-OR  (Standard Design) 20 (40 μL) 200 μL
ALPL-20-RE 20 (40 μL) 200 μL
ALPL-20-GO 20 (40 μL) 200 μL
ALPL-20-GR 20 (40 μL) 200 μL
ALPL-20-AQ 20 (40 μL) 200 μL
ALPL-20-DIG 20 (40 μL) 200 μL
ALPL-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]

Gene Details

Gene Symbol: ALPL

Gene Name: Alkaline Phosphatase, Liver/bone/kidney

Chromosome: CHR1: 21835857-21904905

Locus: 1p36.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ALPL FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ALPL-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping