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ALOX5AP FISH Probe

The ALOX5AP FISH probe is designed to hybridize to the ALOX5AP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ALOX5AP-20-OR  (Standard Design) 20 (40 μL) 200 μL
ALOX5AP-20-RE 20 (40 μL) 200 μL
ALOX5AP-20-GO 20 (40 μL) 200 μL
ALOX5AP-20-GR 20 (40 μL) 200 μL
ALOX5AP-20-AQ 20 (40 μL) 200 μL
ALOX5AP-20-DIG 20 (40 μL) 200 μL
ALOX5AP-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

Gene Details

Gene Symbol: ALOX5AP

Gene Name: Arachidonate 5-lipoxygenase Activating Protein

Chromosome: CHR13: 31287614-31338565

Locus: 13q12.3

Gene Diseases

The ALOX5AP gene has been associated with the following diseases:

Disease Name
2-Hydroxyglutaricaciduria
49,XXXXX Syndrome
Aagenaes Syndrome
Abderhalden-Kaufmann-Lignac Syndrome
Achard Syndrome
Achard-Thiers Syndrome
Acrootoocular Syndrome
Acrorenal Syndrome
Akaba Hayasaka Syndrome
Akesson Syndrome
Aloi Tomasini Isaia Syndrome
Alopecia
Alsing Syndrome
Ameloonychohypohidrotic Syndrome
Angiolipomatosis, Familial
Ansell Bywaters Elderking Syndrome
Arakawa Syndrome 2
AREDYLD Syndrome
Arima Syndrome
Arthritis
Asthma
Atherosclerosis
Aughton Syndrome
Ayazi Syndrome
BADS Syndrome
Baetz-Greenwalt Syndrome
Bagatelle Cassidy Syndrome
Bangstad Syndrome
Banki Syndrome
Banti's Syndrome
Basaran Yilmaz Syndrome
Bassoe Syndrome
Bazopoulou Kyrkanidou Syndrome
Beardwell Syndrome
Beemer Ertbruggen Syndrome
Bellini Chiumello Rimoldi Syndrome
Blepharo-cheilo-dontic Syndrome
Blount Disease
Boerhaave Syndrome
Bone Anteversion
Bone Retroversion
Bonneau Syndrome
Boudhina Yedes Khiari Syndrome
Brachioskeletogenital Syndrome
Brachymesophalangy 2 And 5
Breast Cancer, Familial
Broad-Betalipoproteinemia
Brunoni Syndrome
CAHMR Syndrome
Calabro Syndrome
CAMFAK Syndrome
Campomelia Cumming Type
Cancer
CANOMAD Syndrome
Cantalamessa Baldini Ambrosi Syndrome
Cardiocranial Syndrome
Carrington Syndrome
CATSHL Syndrome
Cerebral Infarction
Cerebrooculonasal Syndrome
Chilaiditi Syndrome
CLAPO Syndrome
Cleidorhizomelic Syndrome
Corneodermatoosseous Syndrome
Coronary Artery Disease
Coxoauricular Syndrome
Cranioacrofacial Syndrome
Craniofaciofrontodigital Syndrome
Craniomicromelic Syndrome
Crome Syndrome
Cryofibrinogenemia, Familial Primary
Cryptotia, Familial
Curatolo Cilio Pessagno Syndrome
Daentl Towsend Siegel Syndrome
Daish Hardman Lamont Syndrome
Daneman Davy Mancer Syndrome
Davenport Donlan Syndrome
Dermatoosteolysis Kirghizian Type
Devriendt Syndrome
Diabetes Mellitus
Dieterich's Disease
Digitorenocerebral Syndrome
Dimauro Disease
Disease
Drachtman Weinblatt Sitarz Syndrome
Faciocardiomelic Syndrome
Faciocardiorenal Syndrome
Fairbank Disease
Familial Dermographism
Familial Hyperbeta- And Prebetalipoproteinemia
Familial Streblodactyly
Fibrosis
FLOTCH Syndrome
Flynn Aird Syndrome
Fountain Syndrome
Franceschini Vardeu Guala Syndrome
Freiberg's Disease
Frontoocular Syndrome
Furlong Syndrome
Furukawa Takagi Nakao Syndrome
Gastrocutaneous Syndrome
Gemignani Syndrome
GEMSS Syndrome
Genoa Syndrome
Giacheti Syndrome
Gigantiform Cementoma, Familial
Gollop Coates Syndrome
GOMBO Syndrome
Granddad Syndrome
Grover's Disease
Gurrieri Sammito Bellussi Syndrome
Hadziselimovic Syndrome
Hagemoser Weinstein Bresnick Syndrome
Halal Syndrome
Hamanishi Ueba Tsuji Syndrome
Hamano Tsukamoto Syndrome
Hapnes Boman Skeie Syndrome
Hardikar Syndrome
Hemorrhage
Herrmann Syndrome
Hersh Podruch Weisskopk Syndrome
Hooft Disease
Hordnes Engebretsen Knudtson Syndrome
Human Balantidiasis
Hunt's Syndrome
Hypercholesterolemia
Hyperreninemic Hypoaldosteronism, Familial, 2
Hypoadrenocorticism, Familial
Hypoxia
Iida Kannari Syndrome
Infarction
Inflammation
Jagell Holmgren Hofer Syndrome
Kaplowitz Bodurtha Syndrome
Kasabach-Merritt Syndrome
Kashani Strom Utley Syndrome
Katsantoni Papadakou Lagoyanni Syndrome
Kennerknecht Sorgo Oberhoffer Syndrome
Kleeblattschaedel Syndrome
Koone Rizzo Elias Syndrome
Kosztolanyi Syndrome
Krasnow Qazi Syndrome
Kuskokwim Disease
Kuzniecky Syndrome
Kyrle Disease
Lachiewicz Sibley Syndrome
Lacrimoauriculodentodigital Syndrome
Lambotte Syndrome
Lelis Syndrome
Lemierre Syndrome
Lyngstadaas Syndrome
Malouf Syndrome
Manouvrier Syndrome
Marchiafava-Bignami Disease
Marsden Syndrome
Massa Casaer Ceulemans Syndrome
May-Thurner Syndrome
Mehes Syndrome
Melhem Fahl Syndrome
Mengel Konigsmark Syndrome
Meralgia Paraesthetica, Familial
Merlob Grunebaum Reisner Syndrome
Meyenburg-Altherr-Uehlinger Syndrome
Microtrauma, Physical
Mirizzi Syndrome
Mollica Pavone Antener Syndrome
MOMES Syndrome
Mononen Karnes Senac Syndrome
Morgellons Disease
Myocardial Infarction
Nasodigitoacoustic Syndrome
Nathalie Syndrome
Neuroblastoma
Neurofaciodigitorenal Syndrome
Nevo Syndrome
Nicolau Syndrome
Nievergelt Syndrome
Nivelon Nivelon Mabille Syndrome
Oculoauriculofrontonasal Syndrome
Oculocerebrocutaneous Syndrome
Oculodental Syndrome Rutherfurd Syndrome
Oculootoradial Syndrome
Oculopalatocerebral Syndrome
Oculopalatoskeletal Syndrome
Oculorenocerebellar Syndrome
Onat Syndrome
Oroticaciduria 1
Oslam Syndrome
Otoonychoperoneal Syndrome
Pachydermodactyly, Familial
Pascual Castroviejo Syndrome
Pashayan Syndrome
Passovoy Factor
Pavone Fiumara Rizzo Syndrome
PHACE Association
Pilotto Syndrome
Piussan Lenaerts Mathieu Syndrome
Plaque, Atherosclerotic
Podder-Tolmie Syndrome
Polythelia, Familial
Postthrombotic Syndrome
Preeyasombat Varavithya Syndrome
Primary Dysautonomias
Propping Zerres Syndrome
Pseudoaminopterin Syndrome
Pseudotrisomy 13 Syndrome
Psoriasis
Pulmonary Fibrosis
Qazi Markouizos Syndrome
Rambaud Galian Syndrome
Ramer Ladda Syndrome
Reactive Angioendotheliomatosis
Reginato Schiapachasse Syndrome
Retinohepatoendocrinologic Syndrome
RHYNS Syndrome
Ribbing Disease
Richards-Rundle Syndrome
Rombo Syndrome
Rosselli-Gulienetti Syndrome
Rudiger Syndrome
Sakoda Complex
Salcedo Syndrome
Sandifer Syndrome
Satoyoshi Syndrome
Schlegelberger Grote Syndrome
Schofer Beetz Bohl Syndrome
Scholte Syndrome
Schrander-Stumpel Theunissen Hulsmans Syndrome
Seaver Cassidy Syndrome
Seemanova Lesny Syndrome
Sener Syndrome
Shapiro Syndrome
Silengo Lerone Pelizza Syndrome
Sillence Syndrome
Sohval Soffer Syndrome
Steinfeld Syndrome
Stroke
Summitt Syndrome
SUNCT Syndrome
Susac Syndrome
Syndrome
Tabatznik Syndrome
Tonoki Syndrome
Translocation, Genetic
Trichodental Syndrome
Trueb Burg Bottani Syndrome
Tsukahara Syndrome
Tucker Syndrome
Upington Disease
Urticaria
Urticaria, Aquagenic
Velofacioskeletal Syndrome
Verloove-Vanhorick Brubakk Syndrome
Volcke Soekarman Syndrome
Walbaum Titran Durieux Crepin Syndrome
Waldmann Disease
Warburton Anyane Yeboa Syndrome
Warman Mulliken Hayward Syndrome
Weismann Netter Syndrome
Wyburn Mason's Syndrome
Yusho Disease
Zazam Sheriff Phillips Syndrome
Zechi-Ceide Syndrome
Zlotogora-Ogur Syndrome
Zuska's Disease

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ALOX5AP FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ALOX5AP-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping