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ALOX5 FISH Probe

The ALOX5 FISH probe is designed to hybridize to the ALOX5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ALOX5-20-OR  (Standard Design) 20 (40 μL) 200 μL
ALOX5-20-RE 20 (40 μL) 200 μL
ALOX5-20-GO 20 (40 μL) 200 μL
ALOX5-20-GR 20 (40 μL) 200 μL
ALOX5-20-AQ 20 (40 μL) 200 μL
ALOX5-20-DIG 20 (40 μL) 200 μL
ALOX5-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Gene Details

Gene Symbol: ALOX5

Gene Name: Arachidonate 5-lipoxygenase

Chromosome: CHR10: 45869628-45941563

Locus: 10q11.21

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ALOX5 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ALOX5-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping