ALIX FISH Probe
The ALIX FISH probe is designed to hybridize to the ALIX gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDCD6IP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PDCD6IP-20-RE | 20 (40 μL) | 200 μL |  |
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| PDCD6IP-20-GO | 20 (40 μL) | 200 μL |  |
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| PDCD6IP-20-GR | 20 (40 μL) | 200 μL |  |
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| PDCD6IP-20-AQ | 20 (40 μL) | 200 μL |  |
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| PDCD6IP-20-DIG | 20 (40 μL) | 200 μL |  |
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| PDCD6IP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
Gene Details
Gene Symbol: PDCD6IP
Gene Name: Programmed Cell Death 6 Interacting Protein
Chromosome: CHR3: 33840065-33911195
Locus: 3p22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALIX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDCD6IP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping