ALDOB FISH Probe
The ALDOB FISH probe is designed to hybridize to the ALDOB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALDOB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ALDOB-20-RE | 20 (40 μL) | 200 μL |  |
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| ALDOB-20-GO | 20 (40 μL) | 200 μL |  |
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| ALDOB-20-GR | 20 (40 μL) | 200 μL |  |
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| ALDOB-20-AQ | 20 (40 μL) | 200 μL |  |
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| ALDOB-20-DIG | 20 (40 μL) | 200 μL |  |
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| ALDOB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
Gene Details
Gene Symbol: ALDOB
Gene Name: Aldolase, Fructose-bisphosphate B
Chromosome: CHR9: 104182841-104198062
Locus: 9q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALDOB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALDOB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping