ALAS1 Break Apart FISH Probe
Empire Genomics’ ALAS1 Break Apart FISH Probe is designed to flank the ALAS1 gene and is typically used for detecting ALAS1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALAS1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ALAS1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ALAS1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ALAS1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ALAS1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ALAS1BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ALAS1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ALAS1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ALAS1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: ALAS1
Gene Name: 5'-aminolevulinate Synthase 1
Chromosome: CHR3: 52232115-52248343
Locus: 3p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: ALAS1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALAS1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping