ALAD FISH Probe
The ALAD FISH probe is designed to hybridize to the ALAD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALAD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ALAD-20-RE | 20 (40 μL) | 200 μL |  |
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| ALAD-20-GO | 20 (40 μL) | 200 μL |  |
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| ALAD-20-GR | 20 (40 μL) | 200 μL |  |
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| ALAD-20-AQ | 20 (40 μL) | 200 μL |  |
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| ALAD-20-DIG | 20 (40 μL) | 200 μL |  |
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| ALAD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: ALAD
Gene Name: Aminolevulinate Dehydratase
Chromosome: CHR9: 116148591-116163618
Locus: 9q32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALAD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALAD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping