AKAP13 Break Apart FISH Probe
Empire Genomics’ AKAP13 Break Apart FISH Probe is designed to flank the AKAP13 gene and is typically used for detecting AKAP13 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AKAP13BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AKAP13BA-20-AQOR | 20 (40 μL) | 200 μL |
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| AKAP13BA-20-GOGR | 20 (40 μL) | 200 μL |
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| AKAP13BA-20-GORE | 20 (40 μL) | 200 μL |
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| AKAP13BA-20-GRGO | 20 (40 μL) | 200 μL |
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| AKAP13BA-20-GROR | 20 (40 μL) | 200 μL |
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| AKAP13BA-20-GRRE | 20 (40 μL) | 200 μL |
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| AKAP13BA-20-REGO | 20 (40 μL) | 200 μL |
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| AKAP13BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: AKAP13
Gene Name: A-kinase Anchoring Protein 13
Chromosome: CHR15: 85923870-86292586
Locus: 15q25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AKAP13 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AKAP13-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping