AKAP-13 FISH Probe
The AKAP-13 FISH probe is designed to hybridize to the AKAP-13 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AKAP13-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AKAP13-20-RE | 20 (40 μL) | 200 μL |  |
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| AKAP13-20-GO | 20 (40 μL) | 200 μL |  |
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| AKAP13-20-GR | 20 (40 μL) | 200 μL |  |
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| AKAP13-20-AQ | 20 (40 μL) | 200 μL |  |
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| AKAP13-20-DIG | 20 (40 μL) | 200 μL |  |
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| AKAP13-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: AKAP13
Gene Name: A-kinase Anchoring Protein 13
Chromosome: CHR15: 85923870-86292586
Locus: 15q25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AKAP-13 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AKAP13-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping