AIFM1 FISH Probe
The AIFM1 FISH probe is designed to hybridize to the AIFM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AIFM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AIFM1-20-RE | 20 (40 μL) | 200 μL |  |
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| AIFM1-20-GO | 20 (40 μL) | 200 μL |  |
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| AIFM1-20-GR | 20 (40 μL) | 200 μL |  |
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| AIFM1-20-AQ | 20 (40 μL) | 200 μL |  |
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| AIFM1-20-DIG | 20 (40 μL) | 200 μL |  |
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| AIFM1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: AIFM1
Gene Name: Apoptosis Inducing Factor Mitochondria Associated 1
Chromosome: CHRX: 129263337-129299861
Locus: Xq26.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AIFM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AIFM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping