AHD-M1 FISH Probe
The AHD-M1 FISH probe is designed to hybridize to the AHD-M1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALDH2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ALDH2-20-RE | 20 (40 μL) | 200 μL |  |
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| ALDH2-20-GO | 20 (40 μL) | 200 μL |  |
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| ALDH2-20-GR | 20 (40 μL) | 200 μL |  |
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| ALDH2-20-AQ | 20 (40 μL) | 200 μL |  |
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| ALDH2-20-DIG | 20 (40 μL) | 200 μL |  |
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| ALDH2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]
Gene Details
Gene Symbol: ALDH2
Gene Name: Aldehyde Dehydrogenase 2 Family (mitochondrial)
Chromosome: CHR12: 112204690-112247789
Locus: 12q24.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AHD-M1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALDH2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping