AGT Break Apart FISH Probe
Empire Genomics’ AGT Break Apart FISH Probe is designed to flank the AGT gene and is typically used for detecting AGT rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AGTBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| AGTBA-20-AQOR | 20 (40 μL) | 200 μL |
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| AGTBA-20-GOGR | 20 (40 μL) | 200 μL |
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| AGTBA-20-GORE | 20 (40 μL) | 200 μL |
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| AGTBA-20-GRGO | 20 (40 μL) | 200 μL |
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| AGTBA-20-GRRE | 20 (40 μL) | 200 μL |
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| AGTBA-20-ORGR | 20 (40 μL) | 200 μL |
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| AGTBA-20-REGO | 20 (40 μL) | 200 μL |
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| AGTBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: AGT
Gene Name: Angiotensinogen
Chromosome: CHR1: 230838271-230850336
Locus: 1q42.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AGT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AGT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping