AGT FISH Probe
The AGT FISH probe is designed to hybridize to the AGT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AGT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AGT-20-RE | 20 (40 μL) | 200 μL |  |
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| AGT-20-GO | 20 (40 μL) | 200 μL |  |
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| AGT-20-GR | 20 (40 μL) | 200 μL |  |
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| AGT-20-AQ | 20 (40 μL) | 200 μL |  |
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| AGT-20-DIG | 20 (40 μL) | 200 μL |  |
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| AGT-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: AGT
Gene Name: Angiotensinogen
Chromosome: CHR1: 230838271-230850336
Locus: 1q42.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AGT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AGT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping