AGS4 FISH Probe
The AGS4 FISH probe is designed to hybridize to the AGS4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RNASEH2A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RNASEH2A-20-RE | 20 (40 μL) | 200 μL |  |
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| RNASEH2A-20-GO | 20 (40 μL) | 200 μL |  |
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| RNASEH2A-20-GR | 20 (40 μL) | 200 μL |  |
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| RNASEH2A-20-AQ | 20 (40 μL) | 200 μL |  |
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| RNASEH2A-20-DIG | 20 (40 μL) | 200 μL |  |
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| RNASEH2A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
Gene Details
Gene Symbol: RNASEH2A
Gene Name: Ribonuclease H2 Subunit A
Chromosome: CHR19: 12917427-12924462
Locus: 19p13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AGS4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RNASEH2A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping