AGR2 FISH Probe
The AGR2 FISH probe is designed to hybridize to the AGR2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AGR2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AGR2-20-RE | 20 (40 μL) | 200 μL |  |
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| AGR2-20-GO | 20 (40 μL) | 200 μL |  |
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| AGR2-20-GR | 20 (40 μL) | 200 μL |  |
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| AGR2-20-AQ | 20 (40 μL) | 200 μL |  |
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| AGR2-20-DIG | 20 (40 μL) | 200 μL |  |
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| AGR2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: AGR2
Gene Name: Anterior Gradient 2, Protein Disulphide Isomerase Family Member
Chromosome: CHR7: 16832263-16844738
Locus: 7p21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AGR2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AGR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping