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AF15Q14 FISH Probe

The AF15Q14 FISH probe is designed to hybridize to the AF15Q14 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KNL1-20-OR  (Standard Design) 20 (40 μL) 200 μL
KNL1-20-RE 20 (40 μL) 200 μL
KNL1-20-GO 20 (40 μL) 200 μL
KNL1-20-GR 20 (40 μL) 200 μL
KNL1-20-AQ 20 (40 μL) 200 μL
KNL1-20-DIG 20 (40 μL) 200 μL
KNL1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11;15)(q23;q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jan 2013]

Gene Details

Gene Symbol: KNL1

Gene Name: Kinetochore Scaffold 1

Chromosome: CHR15: 40594011-40664341

Locus: 15q15.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: AF15Q14 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: KNL1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping