ADSL Break Apart FISH Probe
Empire Genomics’ ADSL Break Apart FISH Probe is designed to flank the ADSL gene and is typically used for detecting ADSL rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADSLBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADSLBA-20-AQOR | 20 (40 μL) | 200 μL |
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| ADSLBA-20-GOGR | 20 (40 μL) | 200 μL |
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| ADSLBA-20-GORE | 20 (40 μL) | 200 μL |
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| ADSLBA-20-GRGO | 20 (40 μL) | 200 μL |
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| ADSLBA-20-GROR | 20 (40 μL) | 200 μL |
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| ADSLBA-20-GRRE | 20 (40 μL) | 200 μL |
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| ADSLBA-20-REGO | 20 (40 μL) | 200 μL |
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| ADSLBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: ADSL
Gene Name: Adenylosuccinate Lyase
Chromosome: CHR22: 40742503-40762575
Locus: 22q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ADSL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ADSL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping