ADRA2C FISH Probe
The ADRA2C FISH probe is designed to hybridize to the ADRA2C gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADRA2C-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ADRA2C-20-RE | 20 (40 μL) | 200 μL |  |
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| ADRA2C-20-GO | 20 (40 μL) | 200 μL |  |
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| ADRA2C-20-GR | 20 (40 μL) | 200 μL |  |
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| ADRA2C-20-AQ | 20 (40 μL) | 200 μL |  |
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| ADRA2C-20-DIG | 20 (40 μL) | 200 μL |  |
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| ADRA2C-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ADRA2C
Gene Name: Adrenoceptor Alpha 2C
Chromosome: CHR4: 3768295-3770253
Locus: 4p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ADRA2C FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ADRA2C-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping