ADMCKD FISH Probe
The ADMCKD FISH probe is designed to hybridize to the ADMCKD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MUC1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MUC1-20-RE | 20 (40 μL) | 200 μL |  |
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| MUC1-20-GO | 20 (40 μL) | 200 μL |  |
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| MUC1-20-GR | 20 (40 μL) | 200 μL |  |
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| MUC1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MUC1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MUC1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: MUC1
Gene Name: Mucin 1, Cell Surface Associated
Chromosome: CHR1: 155158299-155162706
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ADMCKD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MUC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping