ADGRB1 FISH Probe
The ADGRB1 FISH probe is designed to hybridize to the ADGRB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADGRB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ADGRB1-20-RE | 20 (40 μL) | 200 μL |  |
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| ADGRB1-20-GO | 20 (40 μL) | 200 μL |  |
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| ADGRB1-20-GR | 20 (40 μL) | 200 μL |  |
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| ADGRB1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ADGRB1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ADGRB1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ADGRB1
Gene Name: Adhesion G Protein-coupled Receptor B1
Chromosome: CHR8: 142449702-142545008
Locus: 8q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ADGRB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ADGRB1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping