ADCADN FISH Probe
The ADCADN FISH probe is designed to hybridize to the ADCADN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DNMT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DNMT1-20-RE | 20 (40 μL) | 200 μL |  |
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| DNMT1-20-GO | 20 (40 μL) | 200 μL |  |
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| DNMT1-20-GR | 20 (40 μL) | 200 μL |  |
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| DNMT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DNMT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DNMT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: DNMT1
Gene Name: DNA Methyltransferase 1
Chromosome: CHR19: 10244021-10305755
Locus: 19p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ADCADN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DNMT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping