ADAMTS5 Break Apart FISH Probe
Empire Genomics’ ADAMTS5 Break Apart FISH Probe is designed to flank the ADAMTS5 gene and is typically used for detecting ADAMTS5 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADAMTS5BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADAMTS5BA-20-AQOR | 20 (40 μL) | 200 μL |
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| ADAMTS5BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ADAMTS5BA-20-GORE | 20 (40 μL) | 200 μL |
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| ADAMTS5BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ADAMTS5BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ADAMTS5BA-20-ORGR | 20 (40 μL) | 200 μL |
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| ADAMTS5BA-20-REGO | 20 (40 μL) | 200 μL |
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| ADAMTS5BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: ADAMTS8
Gene Name: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8
Chromosome: CHR11: 130274817-130298539
Locus: 11q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ADAMTS5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ADAMTS8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping