AD-018 FISH Probe
The AD-018 FISH probe is designed to hybridize to the AD-018 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DPH5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DPH5-20-RE | 20 (40 μL) | 200 μL |  |
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| DPH5-20-GO | 20 (40 μL) | 200 μL |  |
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| DPH5-20-GR | 20 (40 μL) | 200 μL |  |
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| DPH5-20-AQ | 20 (40 μL) | 200 μL |  |
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| DPH5-20-DIG | 20 (40 μL) | 200 μL |  |
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| DPH5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: DPH5
Gene Name: Diphthamide Biosynthesis 5
Chromosome: CHR1: 101455179-101491362
Locus: 1p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AD-018 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DPH5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping