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ACVR2B FISH Probe

The ACVR2B FISH probe is designed to hybridize to the ACVR2B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ACVR2B-20-OR  (Standard Design) 20 (40 μL) 200 μL
ACVR2B-20-RE 20 (40 μL) 200 μL
ACVR2B-20-GO 20 (40 μL) 200 μL
ACVR2B-20-GR 20 (40 μL) 200 μL
ACVR2B-20-AQ 20 (40 μL) 200 μL
ACVR2B-20-DIG 20 (40 μL) 200 μL
ACVR2B-20-BIO 20 (40 μL) 200 μL

Gene Summary

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ACVR2B

Gene Name: Activin A Receptor Type 2B

Chromosome: CHR3: 38495789-38534633

Locus: 3p22.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ACVR2B FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ACVR2B-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping