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ACVR1 FISH Probe

The ACVR1 FISH probe is designed to hybridize to the ACVR1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ACVR1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ACVR1-20-RE 20 (40 μL) 200 μL
ACVR1-20-GO 20 (40 μL) 200 μL
ACVR1-20-GR 20 (40 μL) 200 μL
ACVR1-20-AQ 20 (40 μL) 200 μL
ACVR1-20-DIG 20 (40 μL) 200 μL
ACVR1-20-BIO 20 (40 μL) 200 μL

Gene Summary

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ACVR1

Gene Name: Activin A Receptor Type 1

Chromosome: CHR2: 158592957-158732374

Locus: 2q24.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ACVR1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ACVR1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping