ACTL6B Break Apart FISH Probe
Empire Genomics’ ACTL6B Break Apart FISH Probe is designed to flank the ACTL6B gene and is typically used for detecting ACTL6B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ACTL6BBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
ACTL6BBA-20-AQOR | 20 (40 μL) | 200 μL | ||
ACTL6BBA-20-GOGR | 20 (40 μL) | 200 μL | ||
ACTL6BBA-20-GORE | 20 (40 μL) | 200 μL | ||
ACTL6BBA-20-GRGO | 20 (40 μL) | 200 μL | ||
ACTL6BBA-20-GRRE | 20 (40 μL) | 200 μL | ||
ACTL6BBA-20-ORGR | 20 (40 μL) | 200 μL | ||
ACTL6BBA-20-REGO | 20 (40 μL) | 200 μL | ||
ACTL6BBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: ACTL6B
Gene Name: Actin Like 6B
Chromosome: CHR7: 100240725-100254084
Locus: 7q22.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ACTL6B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ACTL6B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping