ACL FISH Probe
The ACL FISH probe is designed to hybridize to the ACL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACLY-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ACLY-20-RE | 20 (40 μL) | 200 μL |  |
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| ACLY-20-GO | 20 (40 μL) | 200 μL |  |
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| ACLY-20-GR | 20 (40 μL) | 200 μL |  |
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| ACLY-20-AQ | 20 (40 μL) | 200 μL |  |
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| ACLY-20-DIG | 20 (40 μL) | 200 μL |  |
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| ACLY-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: ACLY
Gene Name: ATP Citrate Lyase
Chromosome: CHR17: 40023178-40075272
Locus: 17q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ACL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ACLY-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping