AC FISH Probe
The AC FISH probe is designed to hybridize to the AC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASAH1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ASAH1-20-RE | 20 (40 μL) | 200 μL |  |
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| ASAH1-20-GO | 20 (40 μL) | 200 μL |  |
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| ASAH1-20-GR | 20 (40 μL) | 200 μL |  |
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| ASAH1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ASAH1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ASAH1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: ASAH1
Gene Name: N-acylsphingosine Amidohydrolase 1
Chromosome: CHR8: 17913924-17942507
Locus: 8p22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ASAH1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping