ABI2 Break Apart FISH Probe
Empire Genomics’ ABI2 Break Apart FISH Probe is designed to flank the ABI2 gene and is typically used for detecting ABI2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABI2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABI2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| ABI2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ABI2BA-20-GORE | 20 (40 μL) | 200 μL |
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| ABI2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ABI2BA-20-GROR | 20 (40 μL) | 200 μL |
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| ABI2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ABI2BA-20-REGO | 20 (40 μL) | 200 μL |
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| ABI2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: ABI1
Gene Name: Abl Interactor 1
Chromosome: CHR10: 27035524-27150016
Locus: 10p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ABI2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ABI1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping