ABCG8 FISH Probe
The ABCG8 FISH probe is designed to hybridize to the ABCG8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABCG8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ABCG8-20-RE | 20 (40 μL) | 200 μL |  |
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| ABCG8-20-GO | 20 (40 μL) | 200 μL |  |
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| ABCG8-20-GR | 20 (40 μL) | 200 μL |  |
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| ABCG8-20-AQ | 20 (40 μL) | 200 μL |  |
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| ABCG8-20-DIG | 20 (40 μL) | 200 μL |  |
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| ABCG8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ABCG8
Gene Name: ATP Binding Cassette Subfamily G Member 8
Chromosome: CHR2: 44066102-44105605
Locus: 2p21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ABCG8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ABCG8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping