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ABCD2 FISH Probe

The ABCD2 FISH probe is designed to hybridize to the ABCD2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ABCD2-20-OR  (Standard Design) 20 (40 μL) 200 μL
ABCD2-20-RE 20 (40 μL) 200 μL
ABCD2-20-GO 20 (40 μL) 200 μL
ABCD2-20-GR 20 (40 μL) 200 μL
ABCD2-20-AQ 20 (40 μL) 200 μL
ABCD2-20-DIG 20 (40 μL) 200 μL
ABCD2-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ABCD2

Gene Name: ATP Binding Cassette Subfamily D Member 2

Chromosome: CHR12: 39945021-40013843

Locus: 12q12

Gene Diseases

Our database currently has no diseases associated with the ABCD2 gene.

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ABCD2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ABCD2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping