ABCD2 FISH Probe
The ABCD2 FISH probe is designed to hybridize to the ABCD2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABCD2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ABCD2-20-RE | 20 (40 μL) | 200 μL |  |
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| ABCD2-20-GO | 20 (40 μL) | 200 μL |  |
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| ABCD2-20-GR | 20 (40 μL) | 200 μL |  |
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| ABCD2-20-AQ | 20 (40 μL) | 200 μL |  |
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| ABCD2-20-DIG | 20 (40 μL) | 200 μL |  |
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| ABCD2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ABCD2
Gene Name: ATP Binding Cassette Subfamily D Member 2
Chromosome: CHR12: 39945021-40013843
Locus: 12q12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ABCD2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ABCD2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping