ABCC5 FISH Probe
The ABCC5 FISH probe is designed to hybridize to the ABCC5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABCC5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ABCC5-20-RE | 20 (40 μL) | 200 μL |  |
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| ABCC5-20-GO | 20 (40 μL) | 200 μL |  |
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| ABCC5-20-GR | 20 (40 μL) | 200 μL |  |
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| ABCC5-20-AQ | 20 (40 μL) | 200 μL |  |
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| ABCC5-20-DIG | 20 (40 μL) | 200 μL |  |
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| ABCC5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: ABCC5
Gene Name: ATP Binding Cassette Subfamily C Member 5
Chromosome: CHR3: 183637723-183735727
Locus: 3q27.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ABCC5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ABCC5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping